Experimental Studies on Hemorrhagic Diathesis

Factor 13 deficiency with severe hemorrhagic diathesis.

A HEMORRHAGIC DIATHESIS due to a congenital deficiency of fibrin stabilizing factor (f.s.f.) was first described in 1960 by Duckert et al.1 Five other cases were discovered since, in different cOuntries.2'6 The fibrin stabilizing factor (Lorand-Laki factor, fibrinase of Loewy), known and investigated in vitro for almost 20 years,7-11 was accepted in 1963 as one of the clotting factors-i.e. Fact...

A hemorrhagic diathesis due to a qualitative platelet defect.

Hemorrhagic Diathesis as the Presenting Symptom of Neonatal Cholestasis

A 4-week-old infant presented with a coagulation disorder resulting from a vitamin K deficiency. The vitamin K deficiency was caused by neonatal cholestasis due to biliary atresia. Jaundice, hepatomegaly and pale stools are the predominant presenting symptoms of biliary atresia, none of which were recognized in our patient before admission. However, the patient presented with bleeding caused by...

Hemorrhagic Diathesis in Borrelia recurrentis Infection Imported to Germany

References 1. Amarasinghe A, Kuritsk JN, Letson GW, Margolis HS. Dengue virus infection in Africa. Emerg Infect Dis. 2011;17:1349–54. 2. Leparc-Goffart I, Nougairede A, Cassadou S, Prat C, de Lamballerie X. Chikungunya in the Americas. Lancet. 2014;383:514. http://dx.doi.org/10.1016/S0140-6736(14)60185-9 3. Weaver SC, Reisen WK. Present and future arboviral threats. Antiviral Res. 2010;85:328–4...

Severe thrombocytopenia and hemorrhagic diathesis due to brucellosis.

BACKGROUND We aimed to examine cases of brucellosis that presented with severe thrombocytopenia and hemorrhagic diathesis. METHODS A total of 10 brucellosis cases with severe thrombocytopenia were included in this case-series study. Patients' files were reviewed for their clinical and laboratory findings, as well as clinical outcomes and complications. Platelet counts of < 20,000/mm³ were dia...